Oxidative stress-prompted degeneration of the retinal pigment epithelium (RPE) notably contributes to the onset of age-related macular degeneration (AMD). However, the pathways leading to RPE deterior
Chordin-like-2 (CHRDL2) is a secreted BMP antagonist, with overexpression and genomic variants associated with colorectal cancer (CRC) risk. BMP signalling in the normal intestinal epithelium operates
Reactivation of the gammaherpesviruses Epstein-Barr virus (EBV), Kaposi's sarcoma-associated herpesvirus (KSHV) and murine gammaherpesvirus 68 (MHV68) from latently infected B cells has been linked to
1The positive effect of MK3 on eIF2α phosphorylation was inhibited by MK2.MK2 and/or MK3 altered expression of HSPB1, HSPB6, HSPB8, CHOP, and MNK1, and phosphorylation of HSPB1, eIF2α, and MNK1, in th