CK-4P

CK-4P investigates the impact of Lactobacillus paracasei treatment on the gut microbiota in Clostridioides difficile infection. Fecal samples from mice post-infection were processed using Invitrogen with sequencing on the Ion Torrent NGS System. Analysis via Ion Reporter SW (16S) revealed shifts in microbial taxa dynamics over days 1, 3, and 6, shedding light on the potential of probiotics in modulating gut microbiota during C. difficile infection.The identification of the sample CK-4P:<br>C: Denotes the strain ST-2 of Clostridioides difficile.<br>K: Represents timepoint 2, indicating sampling after treatment.<br>4: Refers to the specific mouse number under investigation.<br>P: Indicates the treatment administered, which in this case is Lactobacillus paracasei.

CK-4P数据集旨在探究副干酪乳杆菌（Lactobacillus paracasei）干预对艰难梭菌（Clostridioides difficile）感染小鼠肠道菌群的影响。研究人员对感染后小鼠的粪便样本采用英潍捷基（Invitrogen）试剂盒进行前处理，并在Ion Torrent下一代测序（NGS）系统上完成测序。通过Ion Reporter SW（16S）软件开展分析后，研究人员观察到感染后第1、3、6天的微生物类群动态变化，为阐明益生菌在艰难梭菌感染期间调控肠道菌群的潜在作用提供了科学依据。样本CK-4P的标识含义如下：
C：代表艰难梭菌菌株ST-2；
K：代表时间点2，即干预后的采样节点；
4：指代本次研究的特定实验小鼠编号；
P：表示所施加的干预措施，本研究中为副干酪乳杆菌（Lactobacillus paracasei）。