Investigate the susceptibility of different livestock breeds to infectious diseases using blood-based in vitro and ex vivo assays - Zebu

Increased animal - and human mobility, population growth and civil unrest, trade, and climate change and environmental/ecological disruption, all constitute major risk factors for geographic expansion of several vector-borne diseases. This part of the PREPARE4VBD project aims to predict diseases susceptibilities of cattle with a different genetic background (Bos indicus versus Bos taurus) employing a blood-based ex vivo platform. Such a platform will be useful and in line with the 3R values to investigate and compare susceptibilities of defined cattle breeds.