Gene expression profile of preclinical arthritis and its modulation by antigen-induced tolerance

ChEBI2011-11-16 更新2026-07-21 收录

关节炎基因表达

免疫耐受调节

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-31314 数据链接链接失效反馈

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资源简介：

Gene expression profile of preclinical arthritis and its modulation by antigen-induced tolerance

创建时间：

2011-11-16

RNA-Seq approaches to understand the role of ARNO/Cyth2 on IL-1beta-stimulated synovial fibroblasts.. RNA-Seq approaches to understand the role of ARNO/Cyth2 on IL-1beta-stimulated synovial fibroblasts.

滑膜成纤维细胞炎症机制

关节炎基因表达

The aim of this study was to explore the role of ARNO, also known as Cyth2, in synovial fibroblasts using NGS-derived transcriptome analysis (RNA-seq). Synovial fibroblasts were isolated from mouse sy

NIAID Data Ecosystem100

Genes identified in robust genome wide approaches with fold-changes and P-values for OA versus preserved cartilage (OA vs P).

关节炎基因表达

软骨差异基因分析

(Ref: reference, where indicated gene was published as OA susceptibility gene; Pval: nominal P-value; FC: fold change; –: not detected on microarray).

NIAID Data Ecosystem60

Tolerogenic Dendritic Cells Engineered with IL-10 and Antigen Control Pathogenic T Cell Responses and Promote Type 1 T Regulatory Cells. Tolerogenic Dendritic Cells Engineered with IL-10 and Antigen Control Pathogenic T Cell Responses and Promote Type 1 T Regulatory Cells

免疫耐受调节

细胞疗法开发

Dendritic cells (DC) play a critical role in the maintenance of tissue homeostasis and in promoting tolerance, thus acting as regulatory cells. Tolerogenic DC (tolDC) represent the cells of choice to

NIAID Data Ecosystem40

Identification of phase-specific arthritis-related genes in mice

关节炎基因表达

小鼠模型分子机制

Rheumatoid arthritis (RA), one of the most common polygenic diseases, is characterized by a chronic, progressive inflammation mainly in joints and has an unknown etiology. Numerous studies have reveal

NIAID Data Ecosystem60

Regulation of Immunological Tolerance by the p53-Inhibitor iASPP

免疫耐受调节

肿瘤免疫

Maintenance of immunological homeostasis between tolerance and autoimmunity is essential for the prevention of human diseases ranging from autoimmune disease to cancer. Accumulating evidence suggests

NIAID Data Ecosystem50

Gene expression profile of preclinical arthritis and its modulation by antigen-induced tolerance

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