FigS2

(A) Body fat percentage of mice on indicated treatment (NC: normal chow, HFD: high fat diet), either with dox (+Dox) or without dox. (B) (Left) Adipose depot weights of mice on indicated treatment (IWAT: inguinal white adipose tissue, ISCW: interscapular white adipose tissue, PGWAT: perigonadal white adipose tissue). (Right) Spleen weight of mice on indicated treatment. Representative studies on P120 males; n ≥ 16 per cohort, repeated ≥ 3 cohorts. Error bars indicate SEM. Statistical significance assessed by two-tailed Student’s t-test. ^*p<0.05, ^**p<0.01, ^***p<0.001.

(A) 不同处理组小鼠的体脂率（NC：正常饲料（normal chow），HFD：高脂饲料（high fat diet）），分别给予多西环素处理（+Dox）与不予多西环素处理。(B) （左图）不同处理组小鼠的脂肪垫重量（IWAT：腹股沟白色脂肪组织（inguinal white adipose tissue），ISCW：肩胛间白色脂肪组织（interscapular white adipose tissue），PGWAT：性腺周白色脂肪组织（perigonadal white adipose tissue））；（右图）不同处理组小鼠的脾脏重量。本研究以P120雄鼠为代表性实验对象；每队列样本量n≥16，实验重复≥3个队列。误差棒代表均值标准误（SEM）。统计学显著性采用双侧Student t检验进行评估。*p<0.05，**p<0.01，***p<0.001。