five

Effect of GPRC5B-deficieny on macrophage function [dataset 2]

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE261586
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To investigate whether loss of GPRC5B affects macrophage function, we generated myeloid-specific Gprc5b knockout mice and then did RNA-seq using bone marrow-derived M0 macrophages to analyze the gene expression profile. Gene expression profiling in bone marrow-derived M0 macrophages from control mice (LysCre-negative;Gprc5b(fl/fl)) and myeloid-specific Gprc5b knockout mice (LysCre+;Gprc5b(fl/fl)) treated with or without LPS 1µg/ml for 6h (triplicates for each condition).
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2025-02-25
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