five

Global cellular biological processes governed by MET amplification

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NIAID Data Ecosystem2026-03-09 收录
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https://www.omicsdi.org/dataset/biostudies-other/S-ECPF-GEOD-65854
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We used microarrays to probe the global programme of gene expression under treatment with c-Met inhibitor and identified distinct classes of up- and down-regulated genes during this process We treated MET addicted EBC-1 and MKN-45 cells with selective c-Met kinase inhibitor SGX-523 at 1uM for 24 and 48 hours, using HCC827 cells with activated c-Met but lacking MET dependency as a negative control
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2016-04-14
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