prse_ACI.arp

This repository contains R code and data for our manuscript:"<b>Hidden zoonotic risk: immunogenetic-pathogen networks shrink in a generalist rodent inhabiting disturbed landscapes</b>"<br>by Ramona Fleischer, Georg Joachim Eibner, Nina Isabell Schwensow, Sofia Paraskevopoulou, Gerd Mayer, Victor Max Corman, Christian Drosten, Kerstin Wilhelm, Alexander Christoph Heni, Simone Sommer and Dominik Werner Schmid<br>In this work we examined the effect of anthropogenic disturbance at the landscape level on neutral genetic diversity and diversity at the important immune gene region of the Major Histocompatibility Complex class II and multiple pathogen infections in a common neotropical rodent generalist, the Tomey's spiny rat (<i>Proechimys semispinosus</i>).<br>The .arp file is the data input file for the arlequin analysis.

本仓库收录了对应研究手稿的R代码与配套数据集，手稿标题为《隐匿的人畜共患病风险：受干扰景观中广食性啮齿类的免疫遗传-病原体网络缩减》（英文原题：*Hidden zoonotic risk: immunogenetic-pathogen networks shrink in a generalist rodent inhabiting disturbed landscapes*），作者包括Ramona Fleischer、Georg Joachim Eibner、Nina Isabell Schwensow、Sofia Paraskevopoulou、Gerd Mayer、Victor Max Corman、Christian Drosten、Kerstin Wilhelm、Alexander Christoph Heni、Simone Sommer与Dominik Werner Schmid。
本研究以新热带区常见广食性啮齿类——托梅棘鼠（*Proechimys semispinosus*）为研究对象，探究了景观尺度的人为干扰对其中性遗传多样性、关键免疫基因区域主要组织相容性复合体II类（Major Histocompatibility Complex class II）的多样性，以及多种病原体感染情况的影响。
本仓库内的.arp文件为Arlequin分析所用的数据输入文件。