Genome-wide expression profiling of the cryptolepine-induced toxicity in Saccharomyces cerevisiae

We have used the budding yeast Saccharomyces cerevisiae to identify genes that may confer sensitivity in vivo to the antimalarial and cytotoxic agent cryptolepine我们以酿酒酵母（Saccharomyces cerevisiae，又称出芽酵母）为实验材料，鉴定可在活体中赋予生物体对隐品碱（cryptolepine，一种抗疟细胞毒剂）敏感性的基因。