SH1045515.10FU

UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.

UNITE 为界定、识别、传播以及处理基于DNA的物种假说（Species Hypotheses，以下简称SH）提供了统一的标准化途径。国际核苷酸序列数据库中的所有真菌内转录间隔区（Internal Transcribed Spacer，以下简称ITS）序列，均通过应用一套动态距离阈值（0.5%~3.0%）被聚类至近似物种级别。所有SH均以数字对象唯一标识符（Digital Object Identifier，以下简称DOI）的形式被赋予唯一且稳定的标识名称，其分类学与生态学注释信息通过分布式、基于网页的第三方注释工作完成核验。每个SH均会结合其内全部序列的鉴定结果，尽可能关联至对应的分类单元名称及其分类层级（如门、纲、目等）。随后将自动或手动选定一条代表序列以表征每个SH。上述代表序列已发布于（https://unite.ut.ee/repository.php），可供科研社区用于本地序列相似性检索、下一代测序分析流程等科研场景。随着公共真菌ITS序列数量的持续增长，该系统及其配套数据将自动完成更新。