Dataset: Host genetic drift and adaptation in the evolution and maintenance of parasite resistance

The experiment investigates the survival of Caenorhabditis elegans host populations when exposed to a bacterial parasite, Serratia marcescens. Exposed host populations were either large (500 individuals) or small (25 or 50 individuals) and were either susceptible or resistant to the disease. Populations of C. elegans were evolved against either heat-killed or live bacteria. After 13 generations of host evolution, we exposed the worms again to the bacteria to determine whether the worms lost, gained, or maintained resistance to the parasite. In this dataset, we counted the number of worms still living after 48 hours post-infection. A proportion of dead hosts was calculated based on the number of worms still alive after 48 hours divided by the number initially infected.

本实验探究了秀丽隐杆线虫（Caenorhabditis elegans）宿主种群在暴露于细菌性寄生虫粘质沙雷氏菌（Serratia marcescens）时的存活状况。暴露处理的宿主种群分为大型（500只个体）与小型（25或50只个体）两个规模梯度，且对该病原菌分别表现为易感或抗性表型。秀丽隐杆线虫种群分别在热灭活细菌或活细菌的环境中进行演化。经过13代宿主演化后，我们再次将线虫暴露于该细菌，以检测线虫是否丧失、获得或维持了对该寄生虫的抗性。本数据集统计了感染后48小时仍存活的线虫个体数量。宿主死亡比例通过感染后48小时存活线虫数与初始感染线虫数的比值计算得到。