Comparison of sweep visual evoked potential of visual acuity and Snellen visual acuity in healthy and amblyopic children

ABSTRACT Purpose: To evaluate the visual acuity of healthy and amblyopic children using sweep visual evoked potential and compare the results with those of Snellen visual acuity testing. Methods: A total of 160 children aged 6-17 years were included in the study. Of these, 104 (65%) were aged 7-17 years old, able to verbally communicate, and did not have any systemic or ocular pathology (Group 1). Group 2 included 56 (35%) children aged 6-17 years, able to verbally communicate, and had strabismus or anisometropic amblyopia whose best corrected visual acuity was between 0.1 and 0.8. All subjects underwent a detailed ophthalmological examination and sweep visual evoked potential measurement. Demographic characteristics, ocular findings, best corrected visual acuity, and sweep visual evoked potential results were recorded. Results: In Group 1, the mean and maximum visual acuity values for sweep visual evoked potential were lower than the Snellen best corrected visual acuity (p<0.001, for both, respectively). Bland-Altman analysis revealed that in Group 1, the distribution of the differences between the Snellen best corrected visual acuity and mean sweep visual evoked potential visual acuity was ±0.11 logMAR, and the distribution of the differences between the Snellen best corrected visual acuity and maximum sweep visual evoked potential visual acuity was ±0.023 logMAR. In Group 2, the mean and maximum sweep visual evoked potential visual acuity were lower than the Snellen best corrected visual acuity (p<0.001 and p=0.009, respectively). Bland-Altman analysis revealed that the distribution of the differences between the Snellen best corrected visual acuity and mean sweep visual evoked potential visual acuity was ±0.16 logMAR, and the distribution of the differences between the Snellen best corrected visual acuity and maximum sweep visual evoked potential visual acuity was ±0.19 logMAR. Conclusions: Sweep visual evoked potential visual acuity measurements have comparable results with Snellen visual acuity measurements. This technique is an objective and reliable method for evaluating visual acuity in children.

摘要

目的：采用扫描视觉诱发电位（sweep visual evoked potential）评估健康儿童与弱视儿童的视力，并将检测结果与斯内伦视力检查（Snellen visual acuity testing）结果进行对比。

方法：本研究共纳入160名6~17岁儿童。其中104名（占比65%）年龄为7~17岁，可配合语言交流，无全身或眼部病理改变，设为第1组。第2组纳入56名（占比35%）6~17岁可配合语言交流的儿童，均患有斜视或屈光参差性弱视，其最佳矫正视力（best corrected visual acuity）介于0.1~0.8之间。所有受试者均接受详细的眼科检查与扫描视觉诱发电位检测，记录其人口统计学特征、眼部检查结果、最佳矫正视力以及扫描视觉诱发电位检测结果。

结果：在第1组中，扫描视觉诱发电位测得的平均视力与最大视力均低于斯内伦最佳矫正视力，两者的p值均<0.001。布兰德-奥特曼（Bland-Altman）分析显示，第1组中斯内伦最佳矫正视力与扫描视觉诱发电位平均视力的差值分布范围为±0.11 logMAR，斯内伦最佳矫正视力与扫描视觉诱发电位最大视力的差值分布范围为±0.023 logMAR。在第2组中，扫描视觉诱发电位测得的平均视力与最大视力均低于斯内伦最佳矫正视力（分别为p<0.001与p=0.009）。布兰德-奥特曼分析显示，第2组中斯内伦最佳矫正视力与扫描视觉诱发电位平均视力的差值分布范围为±0.16 logMAR，斯内伦最佳矫正视力与扫描视觉诱发电位最大视力的差值分布范围为±0.19 logMAR。

结论：扫描视觉诱发电位视力检测结果与斯内伦视力检测结果具有良好的可比性，该技术是一种用于评估儿童视力的客观且可靠的检测方法。