Gene expression data from Gene Expression Omnibus - GSE40292
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下载链接：
https://figshare.com/articles/dataset/GSE40292/2069710/3
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资源简介：
"Genome-wide association studies (GWAS) have been pivotal to increasing our understanding of intestinal disease. However, the mode by which genetic variation results in phenotypic change remains largely unknown, with many associated polymorphisms likely to modulate gene expression. Analyses of expression quantitative trait loci (eQTL) to date indicate that as many as 50% of these are tissue specific. Here we report a comprehensive eQTL scan of intestinal tissue."<br>http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE40292
全基因组关联研究（Genome-wide association studies, GWAS）对深化我们对肠道疾病的认知发挥了关键作用。然而，遗传变异导致表型改变的具体机制仍未完全明确，诸多关联多态性大概率通过调控基因表达实现其功能。截至目前的表达数量性状基因座（expression quantitative trait loci, eQTL）分析表明，其中多达50%的eQTL具有组织特异性。本研究针对肠道组织完成了一项综合的eQTL扫描分析。
http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE40292
提供机构：
figshare
创建时间：
2016-02-22
