wanessa GOES - Table_S1.xlsx

The five largest clusters identified in Leishmania spp. also were identified in <em>L. amazonensis</em>: amastin-like proteins (Cluster 1), dyneins (Cluster 2) glycoprotein GP63 (Cluster 3), ATP-binding cassette protein (Cluster 4), and histone H4 (Cluster 5). Seven copies of the tuzin gene and three of the amastin genes are among the unique genes of L. amazonensis and biological processes related to symbiont modulation of the host process and membrane transport are enriched between genes encoding proteins with unknown function.

在利什曼原虫属（Leishmania spp.）中鉴定得到的五大聚类簇，同样在亚马逊利什曼原虫（Leishmania amazonensis）中被鉴定到：类无鞭毛体蛋白（amastin-like proteins，Cluster 1）、动力蛋白（dyneins，Cluster 2）、糖蛋白GP63（Cluster 3）、ATP结合盒式蛋白（ATP-binding cassette protein，Cluster 4）以及组蛋白H4（histone H4，Cluster 5）。亚马逊利什曼原虫的特有基因中包含7个tuzin基因（tuzin gene）拷贝与3个无鞭毛体蛋白基因拷贝；在编码功能未知蛋白的基因之间，与共生体调控宿主过程及膜转运相关的生物学过程显著富集。