iPSCORE Analysis: Early Developmental Regulatory Variation Mashr Results

This file contains the mashr results run on the three early developmental iPSCORE tissues and 47 adult GTEx tissues. We used mashr to calculate the tissue-specificity of pairs of eGenes and their eQTL lead variants across all 50 tissues. The file contains the following columns; <b>gene_variant </b>the space-separated identifier for the Gencode gene ID and the eQTL lead variant, <b>ntissues_tested</b> the total number of tissues that the gene_variant was tested in, <b>ntissues_significant</b> the total number of tissues that the gene_variant was significant (local false sign rate [LFSR] &lt; 0.05], <b>nipscore_tested</b> the number of iPSCORE tissues that the gene_variant was tested in, <b>ngtex_tested </b>the number of GTEx tissues that the gene_variant was tested in. The remaining columns contain the mashr-calculated LFSR values for the three iPSCORE tissues and 47 GTEx tissues.

本文件包含针对3种早期发育阶段iPSCORE组织与47种成人GTEx组织执行mashr分析所得的结果。我们采用mashr方法，计算了全部50种组织中，表达数量性状基因（eGene）与其表达数量性状位点（eQTL）先导变异组成的配对的组织特异性。
该文件包含以下列：
**gene_variant**：由Gencode基因ID与eQTL先导变异以空格分隔组成的标识符；
**ntissues_tested**：该基因-变异对参与检测的组织总数量；
**ntissues_significant**：该基因-变异对达到显著性水平的组织总数量（局部假符号率[LFSR] < 0.05）；
**nipscore_tested**：该基因-变异对参与检测的iPSCORE组织数量；
**ngtex_tested**：该基因-变异对参与检测的GTEx组织数量。
其余列均存储了针对3种iPSCORE组织与47种GTEx组织，经mashr计算得到的LFSR值。