Crystal structure of PYK2 complexed with PF-2318841
收藏Protein Data Bank Japan2023-12-27 更新2026-03-21 收录
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Crystal structure of PYK2 complexed with PF-2318841 Descriptor: 5-{[4-{[2-(pyrrolidin-1-ylsulfonyl)benzyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-1,3-dihydro-2H-indol-2-one, PHOSPHATE ION, Protein tyrosine kinase 2 beta Authors: Han, S. Deposit date: 2008-10-07 Release date: 2009-06-23 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Trifluoromethylpyrimidine-based inhibitors of proline-rich tyrosine kinase 2 (PYK2): structure-activity relationships and strategies for the elimination of reactive metabolite formation. Bioorg.Med.Chem.Lett., 18, 2008
创建时间：
2008-10-07
