The synthesis and diversification of a densely functionalized azetidine ring system to gain access to a wide variety of fused, bridged, and spirocyclic ring systems is described. The in vitro physicoc
Repeated dose 14-day toxicity study in adult male rats (Rattus norvegicus), Wistar strain, using chemical compound FP015NN, administered daily orally, sponsored by Novo Nordisk A/S, funded by European
While screening off-target effects of rigid (N)-methanocarba-adenosine 5′-methylamides as A3 adenosine receptor (AR) agonists, we discovered μM binding hits at the δ-opioid receptor (DOR) and transloc
