Skeletal muscle phenotype of the DE50-MD dog: picrosirius red

This dataset contains all picrosirius red histology data used in the manuscript <strong>The skeletal muscle phenotype of the DE50-MD dog model of Duchenne muscular dystrophy</strong> <br> Included are: 1) all raw images (separated by staining batch) for both longitudinal vastus lateralis and post-mortem multiple muscles (images in .tif format) These are subdivided into three .zip files for convenience (labelled appropriately) 2) quantitative 'fibrosis fraction' values derived from thos images, as per-image values and mean per-sample values, along with a sample key. This is provided as a single excel spreadsheet. <br> All quantitative analysis used the methods described in <strong>Rapid histological quantification of muscle fibrosis and lysosomal activity using the HSB colour space</strong> https://www.biorxiv.org/content/10.1101/2022.08.02.502489v1 <br> Also included is a data key file (excel format) containing details of every variable and sample name used in these (and other) analyses

本数据集包含发表于论文《杜氏肌营养不良症DE50-MD犬模型的骨骼肌表型》（The skeletal muscle phenotype of the DE50-MD dog model of Duchenne muscular dystrophy）的所有天狼星红（picrosirius red）染色组织学数据。<br>包含内容如下：1）所有原始图像（按染色批次分组），涵盖纵向股外侧肌样本及死后多部位肌肉样本，图像格式为.tif。为便于使用，这些图像被分为3个命名恰当的压缩包（.zip格式）。2）基于上述图像推导得到的定量“纤维化分数”数据，包含单张图像的纤维化分数值、各样本的平均纤维化分数值，以及样本对应键表，该数据集以单个Excel电子表格形式提供。<br>所有定量分析均采用《基于HSB色彩空间快速定量分析肌肉纤维化与溶酶体活性》（Rapid histological quantification of muscle fibrosis and lysosomal activity using the HSB colour space）一文中所述方法，原文链接：https://www.biorxiv.org/content/10.1101/2022.08.02.502489v1<br>本数据集还附带一份Excel格式的数据键表，其中详细记载了本次及其他分析中使用的全部变量与样本名称。