lnCeDB

lnCeDB provides a database of human lncRNAs (from GENCODE 19 version) that can potentially act as ceRNAs. The putative mRNA targets of human miRNAs and the targets mapped to AGO clipped regions are collected from TargetScan and StarBase respectively. To find out the likelihood of an lncRNA-mRNA pair for actually being ceRNA, ceRNA score is calculated and the P-value for each ceRNA pair is determined. It houses miRNA targets on 22,286 lncRNAs out of 25,978 lncRNA transcripts in GENCODE 19.

lnCeDB 是一个收录可作为潜在内源竞争RNA（competing endogenous RNA，ceRNA）的人类长链非编码RNA（long non-coding RNA，lncRNA）的数据库，其数据来源于GENCODE 19版本。该数据库分别从TargetScan和StarBase中搜集了人类微小RNA（microRNA，miRNA）的推定mRNA靶标，以及映射至AGO剪切区域的靶标。为评估某一lncRNA-mRNA配对实际作为ceRNA的可能性，本数据库计算了ceRNA评分，并确定了每一对ceRNA的P值。该数据库涵盖了GENCODE 19版本中25978条lncRNA转录本里的22286条lncRNA上的miRNA靶标信息。