A major confounding factor for defining disease-specific molecular signatures is the variation in handling and processing of clinical samples. To address this, we assessed how the plasma proteome and
Targeted proteomics offers high precision, reproducibility and multiplexing capabilities for quantifying proteins in complex biological samples, making the technology into a powerful tool for biomarke
This table summarizes the results of the stability selection in terms of the selection frequency of all Olink biomarkers in each scenario and each mboost model (glmboost and gamboost). The asterisked
Additional file 10. Stability of multi-locus signatures. Results of Fisher’s exact test to determine the significance of the overlap between the original multi-locus signature and the stability signat
