A novel Menin-MLL inhibitor induces specific chromatin changes and eradicates disease in models of MLL-rearranged leukemia [RNA-Seq II]

Using 3-end RNA-seq followed by digital gene expression analyses we assessed genes that change expression upon genetic loss of MEN1 for 6 days in triplicates of samples. Overall design: Using 3-end RNA-seq followed by digital gene expression analyses we assessed genes that change expression after knock-out MEN1 at 6 days