Nuclear Receptor Corepressor 1 (NCoR1) deletion changed the expression profile in cardiomyocytes

NCoR1 played an important role in regulating the expression of many genes. We were wondering what kinds of genes the NCoR1 would regulate in cardiomyocytes. Therefore we generated the cardiomyocyte-specific NCoR1 knockout mice (CMNKO). Then we tried to analyze gene expression of left ventricular from littermate control (LC) and CMNKO mice with an unbiased way. Therefore the samples from left ventricular were subjected RNA-sequencing. LV samples were collected from littermate control (LC) and cardiomyocyte-specific NCoR1 knockout (CMNKO) mice at the age of 2 months. Then the samples were sent for RNA sequencing.