Crystal structure of Dot1L in complex with inhibitor CPD5 [N-(2,6-dichlorophenyl)-4-methoxy-N-methylquinolin-6-amine]
收藏Protein Data Bank Japan2024-01-10 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/5dtr
下载链接
链接失效反馈官方服务：
资源简介：
Crystal structure of Dot1L in complex with inhibitor CPD5 [N-(2,6-dichlorophenyl)-4-methoxy-N-methylquinolin-6-amine] Descriptor: Histone-lysine N-methyltransferase, H3 lysine-79 specific, N-(2,6-dichlorophenyl)-4-methoxy-N-methylquinolin-6-amine Authors: Scheufler, C, Be, C, Moebitz, H, Stauffer, F. Deposit date: 2015-09-18 Release date: 2016-06-15 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.34 Å) Cite: Optimization of a Fragment-Based Screening Hit toward Potent DOT1L Inhibitors Interacting in an Induced Binding Pocket. Acs Med.Chem.Lett., 7, 2016
创建时间：
2015-09-18
