Immunoreactivity and Molecular Dynamics of arginine kinase wild type from tick Rhipicephalus sanguineus and a mutant E1

The brown dog tick Rhipicephalus sanguineus is a significant vector for Rocky Mountain Spotted Fever (RMSF), a disease caused by Rickettsia rickettsii.
We report a data on the effect of the tick bite on the immune response in humans of arginine kinase wild type (WT) from tick Rhipicephalus sanguineus and a mutant E1. Absorbance values ​​obtained by ELISA, Calculation of INDEX Value and statistical analysis data is showed.
Furthermore, predictions of WT and E1 RsAK structures were conducted using ColabFold v1.5.2 software. The impact of the mutation on conformational stability was evaluated through molecular dynamics (MD) simulations.