Observed endpoints at specific time points during the zebrafish early life stage test.

Except for continuous variables, all endpoints were visually evaluated for presence or absence using a binary scoring system.• Indicates at which time points each endpoint was observed.* Indicates which endpoints were significantly affected by at least one of the knockdown conditions when compared to SCMO.† Continuous variable¶ Recognized by normal eye shape resembling younger embryos and/or by less iridiphores at certain timepoint.`Hpf = hours post fertilization.Observed endpoints at specific time points during the zebrafish early life stage test.