Estimates of the association between BDNF and cross-sectional and longitudinal cognitive test scores (change in test score per 1 SD increase in BDNF).

Unadjusted model contained: BDNF (standardized), time, BDNF*time.Adjusted model contained: BDNF (standardized), race, sex, history of myocardial infarction, smoking, platelet count (standardized), APOE ε4, age at enrollment, educationth grade, depression, time, and all covariate interactions with time.Regression model estimates and 95% confidence intervals from linear mixed effects models are provided.