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Placental growth factor as potential target against hepatocellular carcinoma in an orthotopic mouse model.

ChEBI2014-12-23 更新2026-07-21 收录

细胞癌靶向治疗

临床前小鼠模型

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-35289 数据链接链接失效反馈

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Placental growth factor as potential target against hepatocellular carcinoma in an orthotopic mouse model.

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创建时间：

2014-12-23

细胞癌靶向治疗

肿瘤生物标志物

Objective Hepatocellular carcinoma (HCC) is a malignant tumor with high global incidence and mortality rates, characterized by complex pathogenesis and a lack of effective specific therapeutic targets

科学数据银行2025-06-25 更新60

Suppression of AKT Anti-Apoptotic Signaling by a Novel Drug Candidate Results in Growth Arrest and Apoptosis of Hepatocellular Carcinoma Cells

细胞癌靶向治疗

AKT信号通路

Hepatocellular carcinoma (HCC) is the third most common cause of cancer fatalities worldwide, with limited treatment options and five year survival rates of between <5 and 15%. To address this medical

NIAID Data Ecosystem30

DataSheet1_Oncogenic Activation of YAP Signaling Sensitizes Ferroptosis of Hepatocellular Carcinoma via ALOXE3-Mediated Lipid Peroxidation Accumulation.zip

肿瘤铁死亡机制

细胞癌靶向治疗

Ferroptosis, a form of programmed cell death process driven by iron-dependent lipid peroxidation, plays an important role in tumor suppression. Although previous study showed that intracellular Merlin

NIAID Data Ecosystem20

COP1 siRNA knockdown in human Hepatocellular carcinoma cells. Homo sapiens

细胞癌靶向治疗

COP1基因沉默机制

Development of targeted therapeutics for hepatocellular carcinoma (HCC) remains a major challenge. We have previously demonstrated that constitutively photomorphogenic 1 (COP1), which regulates p53 ac

NIAID Data Ecosystem50

DataSheet1_Discovery of a New CDK4/6 and PI3K/AKT Multiple Kinase Inhibitor Aminoquinol for the Treatment of Hepatocellular Carcinoma.ZIP

细胞癌靶向治疗

激酶抑制剂药物发现

Background: Hepatocellular carcinoma (HCC) is a lethal malignancy lacking effective treatment. The Cyclin-dependent kinases 4/6 (CDK4/6) and PI3K/AKT signal pathways play pivotal roles in carcinogenes

NIAID Data Ecosystem20

Placental growth factor as potential target against hepatocellular carcinoma in an orthotopic mouse model.

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