Epitome Model Weights
收藏DataCite Commons2024-01-29 更新2024-08-19 收录
下载链接：
https://figshare.com/articles/dataset/Epitome_Model_Weights/25101548/1
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资源简介：
Model weights for the [epitome model](https://pubmed.ncbi.nlm.nih.gov/34379786/) used to benchmark against Enformer Celltyping. Epitome was trained to predict H3K4me1, H3K4me3, H3K27me3, H3K36me3, H3K9me3 and H3K27ac in this setting and trained on the following cells/tissue types:A549 - epithelial cellGM12878 - B-CellGM23248 - fibroblastGM23338 - iPSCH1 - embryonic stem cellsH9 - embryonic stem cellsHCT116 - colorectal carcinomaHeLa-S3 - Cervical adenocarcinomaHepG2 - hepatocellular carcinomaIMR-90 - fetal lung fibroblastsKarpas-422 - B-cell non-Hodgkin's lymphomaMCF-7 - breast adenocarcinomaOCI-LY7 - B-cell Non-Hodgkin lymphomaPC-9 - lung adenocarcinomaPanc1 - pancreatic carcinoma
本数据集包含用于与Enformer Celltyping开展基准对比测试的epitome模型（epitome model）的模型权重，该模型的相关研究可通过链接https://pubmed.ncbi.nlm.nih.gov/34379786/查阅。该epitome模型在此测试场景中被训练用于预测H3K4me1、H3K4me3、H3K27me3、H3K36me3、H3K9me3及H3K27ac六种组蛋白修饰，训练所涵盖的细胞/组织类型如下：
A549：上皮细胞
GM12878：B细胞
GM23248：成纤维细胞
GM23338：诱导多能干细胞（iPSC）
H1：胚胎干细胞
H9：胚胎干细胞
HCT116：结直肠癌细胞
HeLa-S3：宫颈腺癌细胞
HepG2：肝细胞癌细胞
IMR-90：胎儿肺成纤维细胞
Karpas-422：B细胞非霍奇金淋巴瘤细胞
MCF-7：乳腺腺癌细胞
OCI-LY7：B细胞非霍奇金淋巴瘤细胞
PC-9：肺腺癌细胞
Panc1：胰腺癌细胞
提供机构：
figshare
创建时间：
2024-01-29
