OEX_Lan_1804271132
收藏NIAID Data Ecosystem2026-03-11 收录
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https://www.omicsdi.org/dataset/node/OEX00000019
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资源简介：
Genetic depletion of transcription factor Sox30 using CRISPR-Cas9 gene editing technology leads to defects in spermiogenesis, and uniformly arrested at early round spermatids. Specifically, in the absence of Sox30, proacrosomic vesicles fail to form a single acrosomal organelle. This is correlated with changes in postmeiotic gene expression. 1. Testes were collected from male wild-type mice at postnatal day 21 (P21), and testes depleted of Sox30 were collected from male Sox30 KO mice at P21. 2. Pachytene spermatocytes (PS) and round spermatids (RS) were isolated from wild-type （n=6）and Sox30 KO (n=8) mice at 8-week-old.
创建时间：
2019-05-30
