Crystal structure of human Haspin (GSG2) kinase bound to MU1963

Protein Data Bank Japan2025-03-26 更新2026-04-19 收录

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Crystal structure of human Haspin (GSG2) kinase bound to MU1963 Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 5-(1-methylpyrazol-4-yl)-3-pyridin-4-yl-1~{H}-pyrazolo[1,5-a]pyrimidine, NICKEL (II) ION, ... Authors: Kraemer, A, Paruch, K, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2024-06-05 Release date: 2024-10-16 Last modified: 2025-03-26 Method: X-RAY DIFFRACTION (1.91 Å) Cite: Thieno[3,2-b]pyridine: Attractive scaffold for highly selective inhibitors of underexplored protein kinases with variable binding mode. Angew.Chem.Int.Ed.Engl., 64, 2025

创建时间：

2024-06-05