Lobular carcinoma, NOS - Female, 66 - Tissue image [6260730021882551]

This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 66Clinical description: Tumor of right breast. Core needle biopsy: lobular breast carcinoma.Gender: FemaleDiagnosis:Classification: ICD-O_3.2Classification code: DUCTAL AND LOBULAR NEOPLASMSDiagnosis: Lobular carcinoma, NOSResult of the histopathological examination: Lobular breast carcinoma NHG 2 (3+2+1: 0 mitoses/10 HPF) (e-cadherin-, p120+ cytoplasmic reaction).Sample:Material: FFPECollecting method: Surgical specimenTopography: BREASTOrgan: BREASTTissue: Upper-inner quadrant of breastType of staining: positive/IHCStaining: Not applicableAntibody: E-CadherinTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk

本数据集为格但斯克医科大学（Medical University Gdańsk）采集并存入ZMDL-GUMED数据库的乳腺组织样本病理组织学图像。该样本图像采用Pannoramic 250 3DHistech玻片扫描仪（放大倍数20倍）采集，并以DICOM格式存储。

患者、样本及诊断详细信息如下：
患者基本信息：年龄66岁，女性；临床诊断为右侧乳腺肿瘤；空心针穿刺活检提示乳腺小叶癌。
诊断分类：依据ICD-O_3.2分类标准，归类为导管与小叶肿瘤（DUCTAL AND LOBULAR NEOPLASMS）；具体诊断为非特指型小叶癌（Lobular carcinoma, NOS）；组织病理学检查结果为乳腺小叶癌，诺丁汉组织学分级（Nottingham Histologic Grade, NHG）2级（评分3+2+1：每10个高倍视野（High Power Field, HPF）见0个核分裂象），免疫组化（Immunohistochemistry, IHC）结果显示E-钙粘蛋白（E-Cadherin）阴性、p120胞质阳性。
样本相关信息：样本材质为福尔马林固定石蜡包埋（Formalin-Fixed Paraffin-Embedded, FFPE）样本；采集方式为手术标本；解剖部位为乳腺；具体组织区域为乳腺内上象限；染色类型为免疫组化阳性；染色方案无需适配；所用抗体为E-钙粘蛋白；成像设备为Pannoramic 250 3DHistech，镜头放大倍数20倍；数据来源机构为格但斯克医科大学。