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Additional file 5 of The derepression of transposable elements in lung cells is associated with the inflammatory response and gene activation in idiopathic pulmonary fibrosis

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DataCite Commons2021-06-10 更新2024-07-28 收录
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Additional file 5: Supplemental Table 2. Summary of the differential analysis of the TE families between the IPF patients and the donors in different cells based on SQuIRE and REdiscoverTE analysis. A. Whole-lung (WL) tissue - SQuIRE, B. Alveolar type II (AT2) cells - SQuIRE. C. Alveolar macrophages (AM) - SQuIRE. D. Whole-lung (WL) tissue - REdiscoverTE, E. Alveolar type II (AT2) cells - REdiscoverTE. F. Alveolar macrophages (AM) - REdiscoverTE. The columns represent the repeat classification, the TE expression base mean (baseMean), log2 fold change (log2FoldChange), lfcSE (log fold standard error), stat (Wald statistics; lfc/standard error), p-value, p.adj (BH adjusted p-value). Only significant upregulated families are shown. G. Summary of all changes in REdiscoverTE analysis.

附加文件5:补充表2。本表格汇总了基于SQuIRE与REdiscoverTE两种分析工具,对不同细胞类型中特发性肺纤维化(Idiopathic Pulmonary Fibrosis, IPF)患者与健康供体的转座因子(Transposable Element, TE)家族的差异分析结果。 A. 全肺组织(Whole-lung, WL)——SQuIRE分析; B. 肺泡II型细胞(Alveolar type II, AT2)——SQuIRE分析; C. 肺泡巨噬细胞(Alveolar macrophages, AM)——SQuIRE分析; D. 全肺组织(WL)——REdiscoverTE分析; E. 肺泡II型细胞(AT2)——REdiscoverTE分析; F. 肺泡巨噬细胞(AM)——REdiscoverTE分析。 表格各列依次对应:重复序列分类、TE表达基础均值(baseMean)、log2倍变化(log2FoldChange)、log2倍变化标准误(lfcSE)、Wald检验统计量(stat,即log2倍变化值与标准误的比值)、p值(p-value)、经Benjamini-Hochberg(BH)法校正的p值(p.adj)。本部分仅展示显著上调的TE家族。 G. REdiscoverTE分析中所有差异变化情况的汇总。
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2021-06-10
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