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Activity-Based Protein Profiling of BRAF Inhibitor Resistance in Melanoma Cell Lines

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https://www.omicsdi.org/dataset/pride/PXD004343
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资源简介:
To investigate mechanisms of resistance to BRAF inhibitor therapy in melanoma, BRAF mutant cell lines have been chronically exposed to BRAFi to create phenotypes with acquired drug resistance. Activity-based protein profiling with desthiobiotinylating ATP probes (ActivX, Thermo) is used to examine the differences between naive and drug-resistant cells.
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2016-12-13
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