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Forced Expression of MIST1 in Hepatocytes

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NIAID Data Ecosystem2026-03-10 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE93612
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MIST1 over-expression has not been analyzed in a cell type that does not express endogenous MIST1. Here, we force-express ectopic MIST1 in the hepatocytes of mouse livers. We extracted mRNA and compared gene expression levels between MIST1-expressing mouse livers to controls. One mouse from each condition (MIST1-expressing and control) was injected with AAV8-TBG-iCre at 7 weeks. Mouse was subsequently sacrificed 2 weeks later and RNA extracted and hybridized on Affymetrix microarrays. Two separate mRNA extracations from separate liver cubes were performed on each mouse
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2018-02-21
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