Mrgpra1 controls neutrophil hyperactivation by balancing N1/N2 switch. Mrgpra1 controls neutrophil hyperactivation by balancing N1/N2 switch

We want to understand the role of Mrgpra1 regulating neutrophil function. Mrgpra1-sufficient and Mrgpra1-deficient mice were infected with Streptococcus pneumoniae and lung neutrophils were flow-sorted 24h later for RNA-seq Overall design: RNA from flow-sorted lung neutrophils (DAPIneg CD11b+Ly6G+)