Supporting data for "Targeting ubiquitin-proteasome system for cancer therapy"

These files are supporting data for Wang Tianyi's Ph.D. thesis, entitled "Targeting ubiquitin-proteasome system for cancer therapy". In this thesis, nanoparticles or prodrugs are developed for ubiquitin-proteasome system-based therapeutic strategies. The data include chemical synthesis of different chemical tools, characterization of the drugs or materials, cellular studies about how these systems influence intracellular pathways, and in vivo studies about how these platforms perform in tumor-bearing mouse models.

本数据集为王天一博士论文的辅助数据，论文题目为《靶向泛素-蛋白酶体系统用于癌症治疗》。该论文中，研究者开发出基于泛素-蛋白酶体系统的纳米颗粒或前药疗法。数据内容涵盖不同化学工具的化学合成、药物或材料的表征、研究这些系统如何影响细胞内信号通路的相关细胞实验，以及这些平台在携带肿瘤的小鼠模型中的体内实验表现。