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CPL302-253 selectivity and potency in kinase assays.

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https://figshare.com/articles/dataset/CPL302-253_selectivity_and_potency_in_kinase_assays_/12701042
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The CLP302-253 IC50 for the enzymatic activity of recombinant α, β, γ and δ PI3K isoforms was determined in ADP-Glo Kinase assay. The assay was performed at least 3 times. The CPL302-253 binding affinity was assessed in KINOMEScan competitive binding assay. Kd were calculated with a standard dose-response curve using the Hill equation.
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2020-07-23
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