Cotranslational signal independent SRP preloading during membrane targeting

Cotranslational targeting into the endoplasmic reticulum (ER) by the Signal Recognition Particle (SRP) is a key event determining polypeptide fate in eukaryotic cells信号识别颗粒（Signal Recognition Particle，SRP）介导的向内质网（endoplasmic reticulum，ER）共翻译靶向，是真核细胞中决定多肽命运的关键事件。