TOP1

ENCODES a protein that exhibits chromatin DNA binding (ortholog); DNA binding (ortholog); DNA binding, bending (ortholog); INVOLVED IN animal organ regeneration (ortholog); cellular response to luteinizing hormone stimulus (ortholog); DNA replication (ortholog); PARTICIPATES IN irinotecan pharmacodynamics pathway; irinotecan pharmacokinetics pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); disease of cellular proliferation (ortholog); Disease Progression (ortholog); FOUND IN dense fibrillar component (ortholog); fibrillar center (ortholog)

编码一种具有染色质DNA结合活性（同源物）；DNA结合（同源物）；DNA结合、弯曲（同源物）；参与动物器官再生（同源物）；细胞对促黄体生成素刺激的响应（同源物）；DNA复制（同源物）；参与伊立替康药效动力学途径；伊立替康药代动力学途径；与自闭症谱系障碍（同源物）相关；细胞增殖疾病（同源物）；疾病进展（同源物）；存在于致密纤维成分（同源物）；纤维中心（同源物）