Proteomic dataset for: The ESCRT protein CHMP5 restricts bone formation by controlling endolysosome-mitochondrion-mediated cell senescence

This is the proteomic dataset of Chmp5-KO versus control periskeletal progenitor cells, as presented in the paper (Figure 6I). The purpose of the experiment was to identify intracellular proteins that are differentially expressed in Chmp5-KO versus control periskeletal progenitor cells, which were obtained from Chmp5Ctsk and wild-type mice, respectively. The dataset includes data for 3 replicates (cells from 3 different animals) in each group., , # Proteomic dataset for \"The ESCRT protein CHMP5 restricts bone formation by controlling endolysosome-mitochondrion-mediated cell senescence\"

Dataset DOI: [10.5061/dryad.cfxpnvxk2](10.5061/dryad.cfxpnvxk2)

## Description of the data and file structure

This is the proteomic dataset for *Chmp5*-KO and control periskeletal progenitor cells. 

### Files and variables

#### File: BTP-20230615-05-07.raw

**Description:** Control periskeletal progenitor cells, sample 1

#### File: BTP-20230615-05-08.raw

**Description:** Control periskeletal progenitor cells, sample 2

#### File: BTP-20230615-05-09.raw

**Description:** Control periskeletal progenitor cells, sample 3

#### File: BTP-20230615-05-10.raw

**Description:** *Chmp5*-KO periskeletal progenitor cells, sample 1

#### File: BTP-20230615-05-11.raw

**Description:** *Chmp5*-KO periskeletal progenitor cells, sample 2

#### File: BTP-20230615-05-12.raw

**Description:** *Chmp5*-KO periskeletal progenitor cells, sample 3

## Code/software...,

本数据集为*Chmp5*-KO与对照组骨膜周祖细胞的蛋白质组数据集，对应已发表论文中的图6I内容。本实验旨在筛选出分别来自Chmp5Ctsk小鼠与野生型小鼠的Chmp5-KO及对照骨膜周祖细胞中差异表达的细胞内蛋白质。本数据集每组包含3次生物学重复（样本分别取自3只不同的动物）。

# 论文《ESCRT蛋白CHMP5通过控制内溶酶体-线粒体介导的细胞衰老限制骨形成》配套蛋白质组数据集

数据集DOI: 10.5061/dryad.cfxpnvxk2

## 数据与文件结构说明

本数据集对应*Chmp5*-KO及对照骨膜周祖细胞的蛋白质组数据。

### 文件与变量

#### 文件：BTP-20230615-05-07.raw
**说明**：对照组骨膜周祖细胞，样本1

#### 文件：BTP-20230615-05-08.raw
**说明**：对照组骨膜周祖细胞，样本2

#### 文件：BTP-20230615-05-09.raw
**说明**：对照组骨膜周祖细胞，样本3

#### 文件：BTP-20230615-05-10.raw
**说明**：*Chmp5*-KO组骨膜周祖细胞，样本1

#### 文件：BTP-20230615-05-11.raw
**说明**：*Chmp5*-KO组骨膜周祖细胞，样本2

#### 文件：BTP-20230615-05-12.raw
**说明**：*Chmp5*-KO组骨膜周祖细胞，样本3

## 代码/软件...