Supplementary Materials. Prognostic and predictive value of microsatellite instability (MSI) status among patients with colorectal cancer

Supplementary figure 1. Overall survival in (A) stage II CRC and (B) stage III patients according to MSI status.<br>Supplementary figure 2. Stage II CRC with high-risk features.<br>Supplementary figure 3. Overall survival in (A) MSI-H and (B) MSI-S stage II CRC patients with highest-risk features according to chemotherapy.<br>Supplementary figure 4. Stage II CRC without high-risk features.<br>Supplementary figure 5. Overall survival in (A) MSI-H stage III CRC patients with low-risk features and (B) MSI-H stage III CRC patients with high-risk features according to chemotherapy.<br>Supplementary figure A. Patient selection.<br>Supplementary figure B. Histogram for raw data and matched data (stage II MSI-H and high-risk features).<br>Supplementary figure C. Histogram for raw data and matched data (stage II MSI-H and without high-risk features).<br>Supplementary figure D. Histogram for raw data and matched data (stage II MSI-S and without high-risk features).<br>Supplementary Table A. Baseline characteristics of MSI-H stage II CRC patients with high-risk features according to chemotherapy after propensity score matching.<br>Supplementary Table B. Baseline characteristics of MSI-H stage II CRC patients without high-risk features according to chemotherapy after propensity score matching.<br>Supplementary Table C. Baseline characteristics of MSI-L stage II CRC patients without high-risk features according to chemotherapy after propensity score matching.<br>Supplementary Table D. Multivariate analysis for MSI known status stage II &amp; III CRC patients.<br>

补充图1：按微卫星不稳定（Microsatellite Instability, MSI）状态分组的（A）II期结直肠癌（Colorectal Cancer, CRC）及（B）III期结直肠癌患者的总生存期；补充图2：伴高危特征的II期结直肠癌；补充图3：按化疗情况分组的、携带最高危特征的（A）高微卫星不稳定（MSI-High, MSI-H）及（B）微卫星稳定（MSI-Stable, MSI-S）II期结直肠癌患者的总生存期；补充图4：无高危特征的II期结直肠癌；补充图5：按化疗情况分组的（A）伴低危特征的高微卫星不稳定III期结直肠癌患者，及（B）伴高危特征的高微卫星不稳定III期结直肠癌患者的总生存期；补充图A：患者筛选流程；补充图B：原始数据与匹配后数据的直方图（II期高微卫星不稳定且伴高危特征亚组）；补充图C：原始数据与匹配后数据的直方图（II期高微卫星不稳定且无高危特征亚组）；补充图D：原始数据与匹配后数据的直方图（II期微卫星稳定且无高危特征亚组）；补充表A：经倾向得分匹配（Propensity Score Matching）后，伴高危特征的高微卫星不稳定II期结直肠癌患者按化疗情况分组的基线特征；补充表B：经倾向得分匹配后，无高危特征的高微卫星不稳定II期结直肠癌患者按化疗情况分组的基线特征；补充表C：经倾向得分匹配后，无高危特征的低水平微卫星不稳定（MSI-Low, MSI-L）II期结直肠癌患者按化疗情况分组的基线特征；补充表D：已知微卫星状态的II期及III期结直肠癌患者的多因素分析