Oxidative stress correlates with more aggressive features in thyroid cancer.

This dataset contains the RAW data for the paper \"Oxidative stress correlates with more aggressive features in thyroid cancer\". In this paper, we investigated the thyroid differentiation score-TDS in malignant and benign thyroid lesions and normal tissues. A custom AmpliSeq RNA expression panel (Illumina) was designed by the GenomeStudio software to detect the expression of 16 thyroid function genes (DIO1, DIO2, DUOX1, DUOX2, FOXE1, GLIS3, NKX21, PAX8, SLC26A4, SLC5A5, SLC5A8, TG, THRA, THRB, TSHR and TPO) and of the housekeeping gene TBP. The mRNA expression level of the 16 thyroid function genes was used to derive the Thyroid Differentiation Score (TDS).

本数据集为论文《氧化应激与甲状腺癌更具侵袭性特征相关》提供原始数据。本研究针对恶性、良性甲状腺病变及正常组织中的甲状腺分化评分（Thyroid Differentiation Score, TDS）展开了探究。研究人员采用GenomeStudio软件设计了定制化AmpliSeq RNA表达组合（Illumina），用于检测16种甲状腺功能基因（DIO1、DIO2、DUOX1、DUOX2、FOXE1、GLIS3、NKX21、PAX8、SLC26A4、SLC5A5、SLC5A8、TG、THRA、THRB、TSHR、TPO）以及管家基因TBP的表达水平。上述16种甲状腺功能基因的mRNA表达水平被用于计算甲状腺分化评分（TDS）。