Data on Endogenous BRP3 Levels in Mouse Plasma Under Feeding and Fasting Conditions

BRP3 is a novel 26-amino acid peptide that circulates in mouse plasma and is regulated by feeding. Using a computational tool, “Peptide Predictor” we identified BRP3 and quantified its levels in mouse plasma through targeted mass spectrometry (MS) using a Thermo LC-ID-X instrument (Thermo Fisher).
Synthesized mouse BRP3 (10 nM, 100 nM, 1 µM) was used as an authentic standard for measuring endogenous BRP3 levels. The dataset includes raw MS files capturing BRP3 levels in mouse plasma under fasting, feeding, and post-oral glucose administration conditions, alongside synthetic standards.

BRP3是一种新型26肽，可在小鼠血浆中循环，并受进食状态调控。本研究通过计算工具「肽预测器（Peptide Predictor）」成功鉴定出BRP3，并借助赛默飞世尔科技（Thermo Fisher）的Thermo LC-ID-X仪器，采用靶向质谱（mass spectrometry, MS）技术对小鼠血浆中的BRP3水平进行定量检测。合成制备的小鼠BRP3（浓度分别为10 nM、100 nM、1 μM）被用作内源性BRP3水平定量检测的确证标准品。本数据集包含禁食、进食及口服葡萄糖给药三种实验条件下，小鼠血浆中BRP3水平的原始质谱文件，同时附带合成标准品的相关检测数据。