SH1037074.10FU

UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.

UNITE提供了一套统一的方法，用于界定、识别、交流及处理基于DNA的物种假说（DNA-based Species Hypotheses，以下简称SH）。国际核酸序列数据库中的所有真菌ITS序列，均通过应用一组动态距离阈值（0.5%~3.0%）聚类至近似物种级别的分类单元。所有物种假说均被赋予以数字对象标识符（Digital Object Identifier，简称DOI）为形式的唯一稳定标识，其分类学与生态学注释信息则通过分布式网络第三方注释工作完成验证。系统会结合某一物种假说下所有序列的鉴定结果，尽可能将其与对应分类单元名称及其分类层级（门、纲、目等）进行关联。系统将选取一条经自动或人工指定的序列，作为该物种假说的代表序列。此类代表序列已发布于https://unite.ut.ee/repository.php，供科学界用于本地序列相似性搜索、下一代测序分析流程等科研场景。随着公共真菌ITS序列数量的增长，该系统与配套数据集将自动完成更新。