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Structure of bifunctional TcDHFR-TS in complex with MTX

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Protein Data Bank Japan2023-08-30 更新2026-03-21 收录
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Structure of bifunctional TcDHFR-TS in complex with MTX Descriptor: 1,2-ETHANEDIOL, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Bifunctional dihydrofolate reductase-thymidylate synthase (DHFR-TS), ... Authors: Schormann, N, Senkovich, O, Chattopadhyay, D. Deposit date: 2008-03-18 Release date: 2009-01-06 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Structure-based approach to pharmacophore identification, in silico screening, and three-dimensional quantitative structure-activity relationship studies for inhibitors of Trypanosoma cruzi dihydrofolate reductase function. Proteins, 73, 2008
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2008-03-18
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