The reasons for evisceration after penetrating keratoplasty between 1995 and 2015

ABSTRACT Purpose: The purpose of this study was to determine the indications and frequency of evisceration after penetrating keratoplasty (PK). Methods: The medical records of all patients who underwent evisceration after PK between January 1, 1995 and December 31, 2015 at Ankara Training and Research Hospital were reviewed. Patient demographics and the surgical indications for PK, diagnosis for evisceration, frequency of evisceration, and the length of time between PK and evisceration were recorded. Results: The frequency of evisceration was 0.95% (16 of 1684), and the mean age of the patients who underwent evisceration was 56.31 ± 14.82 years. The most common indication for PK that resulted in evisceration was keratoconus (37.5%), and the most common underlying cause leading to evisceration was endophthalmitis (56.25%). The interval between PK and evisceration ranged from 9 to 78 months. Conclusions: Although keratoplasty is one of the most successful types of surgery among tissue transplantations, our findings show that it is associated with a possible risk of evisceration.

摘要
目的：本研究旨在明确穿透性角膜移植术（penetrating keratoplasty, PK）术后眼球摘除术（evisceration）的适应证与发生频率。
方法：回顾性分析1995年1月1日至2015年12月31日期间，在安卡拉培训与研究医院接受PK术后行眼球摘除术的所有患者的病历资料。记录患者人口统计学特征、PK的手术适应证、眼球摘除术的诊断依据、眼球摘除术的发生频率，以及PK与眼球摘除术之间的时间间隔。
结果：本研究中，眼球摘除术的发生频率为0.95%（1684例中16例），接受眼球摘除术患者的平均年龄为56.31±14.82岁。导致需行眼球摘除术的最常见PK适应证为圆锥角膜（37.5%），而引发眼球摘除术的最常见基础病因是眼内炎（56.25%）。PK与眼球摘除术之间的时间间隔为9至78个月。
结论：尽管角膜移植术是组织移植领域中最为成功的手术类型之一，但本研究结果显示，该手术仍存在发生眼球摘除术的潜在风险。