A metabolic co-regulator bioinformatics screen reveals that PGC1Î± suppresses prostate cancer metastasis

ChEBI2016-03-16 更新2026-07-12 收录

生物信息学筛选

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数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-75193 数据链接链接失效反馈

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A metabolic co-regulator bioinformatics screen reveals that PGC1Î± suppresses prostate cancer metastasis

创建时间：

2016-03-16

Next generation sequencing showing miRNA profiles of exosomes derived from DHT-treated CAFs and matched ETOH-treated CAFs

外泌体miRNA分析

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Background: Androgen deprivation therapy (ADT) is the backbone of therapy for advanced prostate cancer (PCa). Despite the good initial response, castration resistance and metastatic progression will i

NIAID Data Ecosystem80

MicroRNA expression in DU145 sublines metastatic to lymph nodes. Homo sapiens

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RNA表达谱

Comparison of non-coding RNA profiling by array in sublines of DU145 human prostate cancer cell lines created by in vivo cycling Cell lines created by removal and growth of metastatic human DU145 tumo

NIAID Data Ecosystem20

The evolutionary steps from primary to metastatic prostate cancer are largely uncharted, and the ability to use DNA present in body fluids as correlates of aggregate metastatic status is under-examined. We reconstructed phylogenies in ten prostate cancer patients with fatal disease using deep targeted sequencing of the prostate, adjacent and distant organs, as well as plasma, serum, and cerebrospinal fluid at various time points. A total of 163 samples are studied.

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肿瘤克隆动态

The evolutionary steps from primary tumor to metastasis in prostate cancer are largely uncharted, and the ability to use serum, plasma, and cerebrospinal fluid as a correlate of aggregate metastatic t

NIAID Data Ecosystem10

Additional file 1 of A two-step process for in silico screening to assess the performance of qRTPCR kits against variant strains of SARS-CoV-2

病毒检测技术

生物信息学筛选

Additional file 1.

Figshare2024-02-08 更新30

Knockdown of Akt1/2 by CRISPR/Cas9 suppresses the metastasis of human prostate cancer cells CWR22rv1 in vitro and in vivo. Knockdown of Akt1/2 by CRISPR/Cas9 suppresses the metastasis of human prostate cancer cells CWR22rv1 in vitro and in vivo

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CRISPRi基因编辑

Our findings will initially map out the downstream signal pathways of Akt and AR mutual feedback to regulate CaP metastasis through the study of these scientific assumptions, which will provide target

NIAID Data Ecosystem20

A metabolic co-regulator bioinformatics screen reveals that PGC1Î± suppresses prostate cancer metastasis

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