Histone H2B ubiquitylation and H3 lysine 4 methylation prevent ectopic silencing of euchromatic loci important for the cellular response to heat

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In Saccharomyces cerevisiae, ubiquitylation of histone H2B signals methylation of histone H3 at lysine residues 4 (K4) and 79

在酿酒酵母（Saccharomyces cerevisiae）中，组蛋白H2B（histone H2B）的泛素化（ubiquitylation）可介导组蛋白H3（histone H3）在赖氨酸残基4（K4）与79位的甲基化。