Distal Electrical Stimulation Enhances Neuromuscular Reinnervation and Satellite Cell Differentiation for Functional Recovery

Peripheral nerve injuries cause significant motor deficits, with limited treatment options for full recovery. Distal electrical stimulation (E-stim) shows potential in promoting neuromuscular reinnervation, although its mechanisms remain unclear. This study examines how distal E-stim influences neuromuscular junction reinnervation and Satellite cell activity in denervated muscles.周围神经损伤可引发严重的运动功能缺损，且当前缺乏可实现完全康复的有效治疗方案。远端电刺激（distal electrical stimulation, E-stim）在促进神经肌肉再支配领域展现出潜在应用价值，但其具体作用机制仍有待阐明。本研究旨在探究远端电刺激对失神经支配肌肉内神经肌肉接头再支配以及卫星细胞活性的影响。