Gene expression changes in Ing1- and Gadd45a- single- or double-knockout mouse embryonic fibroblasts
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE115187
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资源简介：
ING1b and GADD45a are nuclear proteins involved in the regulation of cell growth, apoptosis and DNA repair. We previously found that ING1b is required to target GADD45a-mediated active DNA-demethylation via TET1 to specific loci. In order to study the impact of ING1-GADD45a on gene expression, we compared the expression profile of wildtype mouse embryonic fibroblasts (MEFs) with Ing1- and Gadd45a- single- or double-knockout (DKO) MEFs. Gene expression profiling in all 4 genotypes of undifferentiated MEFs in triplicates.
创建时间：
2019-03-19
